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I don't know from my own experience yet, but from reading a lot of other builds and info they were able to tune the E85 the to around the same boost and power as using C16. I should be tuning mine next month but im only at 10:1
 

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Not to thread jack here, but i'm currently having a 5.3L BB stroker being put together, ported head short runner intake, E85, With boost, also looking to make around 1krwhp, and maybe a couple hundered more down the road.. I was planning on running the MMR Stage 3 turbo cams, with 10.1 compression

Would it be beneficial for me to increase the compression further say 10.5 or 11 to 1?
 
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